Gladstone House

Gladstone House is a boutique hotel at 1214 Queen Street West in the Parkdale area of Toronto, Ontario, Canada. Since renovations in the early 2000s, the hotel has become an arts hub in the West Queen West neighbourhood of Toronto. The hotel's restaurant and bar is located on the main floor and is known as Gladstone House Bistro + Bar.

The historic building was originally designed by local architect George Martell Miller in the Richardsonian Romanesque style, and it is one of the oldest hotel buildings still operating as a hotel in Toronto. It was built in 1889 and named for Gladstone Avenue, which is beside the hotel. In June 1973, the City of Toronto assigned a Part IV historical designation to the property.